F. Javier Piedrafita's
PubMed References
Lopez-Hernandez FJ, et al.
Reduced concentrations of serum enhance the antiproliferative activity
of retinoid-related molecules and accelerate the onset of apoptosis.
Biochem Pharmacol., 2003; 65:2021-2030.
Lopez-Hernandez FJ, et al.
Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and
10, and demonstrates that novel anticancer retinoid-related molecules
induce apoptosis via the intrinsic pathway.
Mol Cancer Therapeutics, 2003; 2:255-263.
Bayon Y, et al.
Inhibition of IkB kinase by a new class of retinoid-related anticancer
agents that induce apoptosis.
Mol
Cell Biol 2003; 23(3):1061-1074.
Ortiz, M.A, et al.
Retinoids in combination therapies for the treatment of cancer: Mechanisms
and Perspectives.
Drug Resistance Updates 2002;5(3-4):162-175.
Ortiz, M.A, et al.
Retinoid-related Molecules Induce Cytochrome c Release and Apoptosis
through Activation of c-Jun NH2-Terminal Kinase/p38 Mitogen-activated
Protein Kinases.
Cancer Res 2001;61 8504-8512.
Fanjul AN, et al.
Apoptosis induction and potent antiestrogen receptor-negative
breast cancer activity in vivo by a retinoid antagonist.
Cancer Res. 1998 Oct 15;58(20):4607-10.
Piedrafita FJ, et al.
Retinoid-induced apoptosis and Sp1 cleavage occur independently
of transcription and require caspase activation.
Mol Cell Biol. 1997 Nov;17(11):6348-58.
Piedrafita FJ, et al.
An Alu element in the myeloperoxidase promoter contains a
composite SP1-thyroid hormone-retinoic acid response element.
J Biol Chem. 1996 Jun 14;271(24):14412-20.
Ortiz MA, et al.
TOR: a new orphan receptor expressed in the thymus that
can modulate retinoid and thyroid hormone signals.
Mol Endocrinol. 1995 Dec;9(12):1679-91.
Piedrafita FJ, et al.
Thyroid hormone receptor-beta mutants associated with
generalized resistance to thyroid hormone show defects
in their ligand-sensitive
repression
function.
Mol Endocrinol. 1995 Nov;9(11):1533-48.
Bouterfa HL, et al.
Regulation of H1(0) gene expression by nuclear receptors
through an unusual response element: implications
for regulation of
cell proliferation.
DNA Cell Biol. 1995 Nov;14(11):909-19.
Piedrafita FJ, et al.
Thyroid hormone receptor homodimers can function
as ligand-sensitive repressors.
Mol Endocrinol. 1995 May;9(5):563-78.
Perez RA, et al.
Kinetics of the reversible tight-binding inhibition
of pig liver catechol-O-methyltransferase by
[2-(3,4-dihydroxy-2- nitrophenyl)vinyl]phenyl
ketone.
J Enzyme Inhib. 1994;8(2):123-31.
Salbert G, et al.
Retinoic acid receptors and retinoid X receptor-alpha
down-regulate the transforming growth factor-beta
1 promoter by antagonizing
AP-1 activity.
Mol Endocrinol. 1993 Oct;7(10):1347-56.
Perez RA, et al.
Inhibition of catechol-O-methyltransferase
by 1-vinyl derivatives of nitrocatechols
and nitroguaiacols.
Kinetics of the irreversible
inhibition
by 3-(3-hydroxy-4-methoxy-5-nitro benzylidene)-2,4-pentanedione.
Biochem Pharmacol. 1993 May 25;45(10):1973-81.
Hermann T, et al.
V-erbA requires auxiliary proteins for dominant
negative activity.
Oncogene. 1993 Jan;8(1):55-65.
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