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Charles Spruck's
PubMed References
Selected Publications:
Keller UB, Old JB, Dorsey FC, Nilsson JA, Nilsson L, Maclean KH, Chung
L, Yang C, Spruck C, Boyd K, Reed SI, Cleveland JL.
Myc targets Cks1 to provoke the suppression of p27(Kip1), proliferation
and lymphomagenesis.
EMBO
J. 2007 May 16;26(10):2562-74.
Spruck C, Sun D, Fiegl H, Marth C, Mueller-Holzner E, Goebel G, Widschwendter
M, Reed SI.
Detection of low molecular weight derivatives of cyclin E1 is a function
of cyclin E1 protein levels in breast cancer.
Cancer Res. 2006 Jul 15;66(14):7355-60. Hubalek MM, Widschwendter A, Erdel M, Gschwendtner A, Fiegl HM, Muller
HM, Goebel G, Mueller-Holzner E, Marth C, Spruck CH, Reed SI, Widschwendter
M.
Cyclin
E dysregulation and chromosomal instability in endometrial cancer.
Oncogene. 2004 May 20;23(23):4187-92.
Ekholm-Reed S, Spruck CH, Sangfelt, O, van Drogen F, Mueller-Holzner
E, Widschwendter M, Zetterberg A, and Reed SI.
Mutation of hCdc4
leads to cell cycle deregulation of cyclin E in cancer.
Cancer Res. 2004 Feb 1;64(3):795-800.
Spruck CH, de Miguel M, Smith APL, Ryan A, Stein P, Schultz RM, Lincoln
AJ, Donovan PJ and Reed SI.
Requirement of cks2 for the first
metaphase/anaphase transition of mammalian meiosis.
Science. 2003 Apr 25;300(5619):647-50.
Spruck CH and Strohmaier H.
Seek and destroy: SCF-ligases in
mammalian cell cycle control.
Cell
Cycle. 2002 Jul-Aug;1(4):250-4. Review.
Spruck CH, Strohmaier H, Sangfelt O, Muller HM, Hubalek M, Muller-Holzner
E, Marth C, Widschwendter M, and Reed SI.
hCDC4 gene mutations
in endometrial cancer.
Cancer Res. 2002 Aug 15;62(16):4535-9.
Spruck C, Strohmaier H, Watson M, Smith APL, Ryan A, Krek TW, and Reed
SI.
A CDK-independent function of mammalian Cks1: targeting of
SCFSkp2 to the CDK inhibitor p27Kip1.
Mol Cell. 2001 Mar;7(3):639-50.
Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, and Reed SI.
Human F-box protein hCdc4 targets cyclin E for proteolysis and
is mutated in a breast cancer cell line.
Nature. 2001 Sep 20;413(6853):316-22.
Spruck CH, Won KA, and Reed SI.
Deregulated cyclin E induces
chromosome instability.
Nature. 1999 Sep 16;401(6750):297-300.
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